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However, the abovementioned studies hold a few limitations

In some patients, MRD develops from treatment selection of drug-resistant subclones

Thanks, Linda Lola Thank you so much

It lengthens telomeres beyond the Hayflick limit and normalizes age-related melatonin decline

There are reports which indicate that the severity and incidence of metabolism-associated toxicity of INH increase with the age of the patient (Oscanoa et al., 2023